How long do the effects of the ED meds last? May 30, 2023 22:52 The effects can last up to 36hrs. Results may vary. Related to meds info meds ingredients meds instructions Related articles Do I need to refrigerate these once I receive them? When is the best time to take ED meds? Do you take the whole tab at once? Do ED meds expire? How long does it take for your prescription to be approved?